Estradiol, Sensitive (LC/MS/MS)

CPT: 82670
Hormones

What This Test Measures

Mass spectrometry-based estradiol; more accurate at low levels; preferred for men and children.

Preparation

No fasting required
Draw at a consistent point in your cycle if cycling (typically Day 3 for baseline, or Day 21 for luteal phase progesterone). If on BHRT injections, draw at trough (just before next injection). Results vary significantly by time in cycle.
💬 Patient Community Notes

TIMING: For cycling women, specify cycle day. Day 3 for baseline, day 12–14 for peak. For BHRT: draw at trough before next dose. The sensitive (LC/MS/MS) assay is preferred for men, post-menopausal women, and anyone with low estradiol — standard immunoassay loses accuracy at low levels. BHRT community notes that levels vary widely by delivery method. Symptom correlation matters as much as numbers. These notes reflect common practices in BHRT/functional medicine communities.

Reflects common practices in thyroid, BHRT, and functional medicine communities. This may differ from standard clinical guidelines. Not medical advice — always discuss with your provider.

General guidelines only. Requirements vary by lab and individual. Confirm with your provider before adjusting any medications.

Turnaround Time

Varies by lab

Clinical Notes

Quest Diagnostics Estradiol Sensitive (code 30289); Labcorp Estradiol, Sensitive

ICD-10 Codes

Common diagnosis codes associated with this test. Codes are assigned by your provider.

E28.39Other ovarian dysfunction
N91.2Amenorrhea, unspecified
N95.1Menopausal and female climacteric states
Z78.0Asymptomatic menopausal state

Self-Pay Pricing

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Ulta Lab Tests

Uses Quest Diagnostics network; generally lowest DTC prices; not available in NY, NJ, RI

$30.95Order
Life Extension

Uses Labcorp network; known for supplement company; competitive lab test pricing

$33.00Order
Walk-In Lab

Uses both Quest and Labcorp networks; competitive pricing; broad test selection

$49.00Order
HealthLabs.com

Uses Quest and Labcorp; strong panel bundling; results in 1-3 days

$49.00Order
Request A Test

Uses Quest and Labcorp networks; offers both individual tests and discounted panels

$59.00Order

Lab Codes

Proprietary codes used by each lab for this test.

ARUP Laboratories
0093247(order_code)
LabCorp
140244(order)
Mayo Clinic Labs
FFES(order_code)
Quest Diagnostics
30289(order)

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CPT: 83001

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CPT: 83002

Prolactin

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For informational purposes only

This page is for educational and research purposes only and does not constitute medical advice, diagnosis, or treatment recommendations. ICD-10 and CPT codes are assigned by your healthcare provider. Always consult a qualified healthcare provider before ordering any lab test or making decisions about your health.