Vitamin D, 1,25-Dihydroxy (Active / Calcitriol)
What This Test Measures
Active form of Vitamin D; regulated by kidneys; elevated in sarcoidosis and some granulomatous diseases.
Preparation
NOTE: This test measures ACTIVE vitamin D, not storage vitamin D. It is NOT a substitute for 25-OH vitamin D. Active D can be normal or even high while 25-OH (storage) is depleted — the body compensates by converting more aggressively. The functional medicine community recommends 25-OH as the primary screening test. 1,25-dihydroxy is useful for kidney disease, sarcoidosis, or when 25-OH doesn't explain symptoms. Always interpret alongside 25-OH, calcium, and PTH.
Reflects common practices in thyroid, BHRT, and functional medicine communities. This may differ from standard clinical guidelines. Not medical advice — always discuss with your provider.
General guidelines only. Requirements vary by lab and individual. Confirm with your provider before adjusting any medications.
Turnaround Time
Varies by lab
Clinical Notes
Active form; less useful than 25-OH for assessing D status; elevated in granulomatous disease
ICD-10 Codes
Common diagnosis codes associated with this test. Codes are assigned by your provider.
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Lab Codes
Proprietary codes used by each lab for this test.
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For informational purposes only
This page is for educational and research purposes only and does not constitute medical advice, diagnosis, or treatment recommendations. ICD-10 and CPT codes are assigned by your healthcare provider. Always consult a qualified healthcare provider before ordering any lab test or making decisions about your health.